MetaCyc Pathway: L-tryptophan degradation XIII (reductive Stickland reaction) in Paraburkholderia sabiae LMG 24235

Add experiment(s):


Aspartate transaminase:
L-tryptophan + 2-oxoglutarate→(indol-3-yl)pyruvate + L-glutamate
(EC 2.6.1.1; 2.6.1.27)
QEN71_RS00075
QEN71_RS02890
QEN71_RS03175
QEN71_RS03275
QEN71_RS06560
QEN71_RS08880
QEN71_RS10500
QEN71_RS12205
QEN71_RS12215
QEN71_RS13030
QEN71_RS17025
QEN71_RS18160
QEN71_RS18375
QEN71_RS20720
QEN71_RS21505
QEN71_RS22410
QEN71_RS23125
QEN71_RS23470
QEN71_RS24010
QEN71_RS24645
QEN71_RS30710
QEN71_RS31640
QEN71_RS32300
QEN71_RS36905
QEN71_RS38860
QEN71_RS38900
QEN71_RS38970
Indolelactate dehydrogenase (in reverse):
(indol-3-yl)pyruvate + NADH + H+→(R)-3-(indol-3-yl)lactate + NAD+
(EC 1.1.1.110)
No genes
Cinnamoyl-CoA:phenyllactate CoA-transferase:
(R)-3-(indol-3-yl)lactate + 3-(indol-3-yl)acryloyl-CoA→3-(indol-3-yl)acrylate + (R)-3-(indol-3-yl)lactoyl-CoA
(EC 2.8.3.17)
No genes
3-(indol-3-yl)acrylate + a reduced electron-transfer flavoprotein→3-(1H-indol-3-yl)propanoate + an oxidized electron-transfer flavoprotein + H+ (EC 1.3.8.15)
QEN71_RS06635
(R)-3-(indol-3-yl)lactoyl-CoA→3-(indol-3-yl)acryloyl-CoA + H2O (EC 4.2.1.175)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information