MetaCyc Pathway: 4-oxopentanoate degradation in Paraburkholderia sabiae LMG 24235

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Butyrate--CoA ligase:
4-oxopentanoate + ATP + coenzyme A→4-oxopentanoyl-CoA + AMP + diphosphate (EC 6.2.1.2)
No genes
Butyrate--CoA ligase:
4-hydroxypentanoate + ATP + coenzyme A→4-hydroxypentanoyl-CoA + AMP + diphosphate (EC 6.2.1.2)
No genes
4-oxopentanoyl-CoA + NAD(P)H + H+→4-hydroxypentanoyl-CoA + NAD(P)+ (EC 1.1.1.M44)
No genes
4-hydroxypentanoyl-CoA + ATP→4-(phosphooxy)pentanoyl-CoA + ADP + H+ (EC 2.7.1.M16)
No genes
4-(phosphooxy)pentanoyl-CoA→3-pentenoyl-CoA + phosphate (EC 5.4.4.M2)
No genes
3-pentenoyl-CoA→(2E)-pent-2-enoyl-CoA (EC 5.4.4.M2)
No genes
(2E)-pent-2-enoyl-CoA + H2O→(3R)-3-hydroxypentanoyl-CoA (EC 5.4.4.M2)
No genes
Acetoacetyl-CoA reductase:
(3R)-3-hydroxypentanoyl-CoA + NADP+→3-oxopentanoyl-CoA + NADPH + H+ (EC 1.1.1.36)
QEN71_RS22195
QEN71_RS32115
Acetyl-CoA C-acyltransferase (in reverse):
3-oxopentanoyl-CoA + coenzyme A→propanoyl-CoA + acetyl-CoA (EC 2.3.1.16; 2.3.1.9)
QEN71_RS01125
QEN71_RS02070
QEN71_RS14170
QEN71_RS15980
QEN71_RS18320
QEN71_RS18730
QEN71_RS21880
QEN71_RS22175
QEN71_RS22200
QEN71_RS22970
QEN71_RS27505

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information