MetaCyc Pathway: aromatic biogenic amine degradation (bacteria) in Paraburkholderia sabiae LMG 24235

Add experiment(s):


Octopamine dehydratase:
octopamine→(4-hydroxyphenyl)acetaldehyde + ammonium (EC 4.2.1.87)
No genes
tyramine + an oxidized electron carrier + H2O→(4-hydroxyphenyl)acetaldehyde + ammonium + a reduced two electron carrier
No genes
Monoamine oxidase:
tyramine + dioxygen + H2O→(4-hydroxyphenyl)acetaldehyde + ammonium + hydrogen peroxide (EC 1.4.3.4)
QEN71_RS40200
Monoamine oxidase:
dopamine + dioxygen + H2O→3,4-dihydroxyphenylacetaldehyde + ammonium + hydrogen peroxide (EC 1.4.3.4)
QEN71_RS40200
Synephrine dehydratase:
(R)-synephrine→(4-hydroxyphenyl)acetaldehyde + methylamine (EC 4.2.1.88)
No genes
4-hydroxyphenylacetaldehyde dehydrogenase:
(4-hydroxyphenyl)acetaldehyde + NAD+ + H2O→(4-hydroxyphenyl)acetate + NADH + 2 H+ (EC 1.2.1.53)
No genes
Aldehyde dehydrogenase (NAD(+)):
3,4-dihydroxyphenylacetaldehyde + NAD+ + H2O→(3,4-dihydroxyphenyl)acetate + NADH + 2 H+ (EC 1.2.1.3)
QEN71_RS00050
QEN71_RS07095
QEN71_RS11040
QEN71_RS11670
QEN71_RS13660
QEN71_RS14810
QEN71_RS16945
QEN71_RS19510
QEN71_RS20195
QEN71_RS20440
QEN71_RS20790
QEN71_RS21070
QEN71_RS23580
QEN71_RS24925
QEN71_RS27500
QEN71_RS28765
QEN71_RS31880
QEN71_RS31965
QEN71_RS32565
QEN71_RS34295
QEN71_RS35780
QEN71_RS37085
QEN71_RS38180
QEN71_RS38780
QEN71_RS39635
QEN71_RS40180
QEN71_RS41285
QEN71_RS42030
(4-hydroxyphenyl)acetate + FADH2 + dioxygen→(3,4-dihydroxyphenyl)acetate + FAD + H+ + H2O (EC 1.14.14.9)
QEN71_RS07485
QEN71_RS31130

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information