MetaCyc Pathway: glutathione-mediated detoxification II in Paraburkholderia sabiae LMG 24235

Add experiment(s):


Glutathione transferase:
RX + glutathione→a glutathione-S-conjugate + HX (EC 2.5.1.18)
QEN71_RS00955
QEN71_RS01655
QEN71_RS05335
QEN71_RS05570
QEN71_RS07235
QEN71_RS07950
QEN71_RS09680
QEN71_RS13620
QEN71_RS14980
QEN71_RS15945
QEN71_RS16090
QEN71_RS16255
QEN71_RS16280
QEN71_RS17320
QEN71_RS18225
QEN71_RS23535
QEN71_RS24015
QEN71_RS24045
QEN71_RS26755
QEN71_RS28625
QEN71_RS37945
QEN71_RS38990
QEN71_RS39195
QEN71_RS39455
QEN71_RS39725
a glutathione-S-conjugate[in] + ATP[in] + H2O[in]→a glutathione-S-conjugate[out] + ADP[in] + H+[in] + phosphate[in] (EC 7.6.2.3)
No genes
a glutathione-S-conjugate + H2O→a [γ-glutamyl-L-cysteine]-S-conjugate + glycine (EC 3.4.17.25)
No genes
a glutathione-S-conjugate + H2O→an (L-cysteinylglycine)-S-conjugate + L-glutamate (EC 3.4.19.13)
No genes
a [γ-glutamyl-L-cysteine]-S-conjugate + H2O→an L-cysteine-S-conjugate + L-glutamate (EC 3.4.13.M2)
No genes
an (L-cysteinylglycine)-S-conjugate + H2O→an L-cysteine-S-conjugate + glycine (EC 3.4.13.23)
No genes
an L-cysteine-S-conjugate + malonyl-CoA→an N-malonyl-L-cysteine-S-conjugate + coenzyme A + H+
No genes
Cysteine-S-conjugate beta-lyase:
an L-cysteine-S-conjugate + H2O→a thiol + ammonium + pyruvate (EC 4.4.1.13)
No genes
Thiol S-methyltransferase:
a thiol + S-adenosyl-L-methionine→a methyl thioether + S-adenosyl-L-homocysteine + H+ (EC 2.1.1.9)
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information