MetaCyc Pathway: superpathway of Clostridium acetobutylicum solventogenic fermentation in Paraburkholderia sabiae LMG 24235

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Pyruvate synthase:
pyruvate + coenzyme A + 2 an oxidized ferredoxin [iron-sulfur] cluster→acetyl-CoA + CO2 + H+ + 2 a reduced ferredoxin [iron-sulfur] cluster (EC 1.2.7.1)
No genes
Acetaldehyde dehydrogenase (acetylating) (in reverse):
acetyl-CoA + NADH + H+→acetaldehyde + coenzyme A + NAD+ (EC 1.2.1.10)
No genes
Acetyl-CoA C-acyltransferase:
2 acetyl-CoA→acetoacetyl-CoA + coenzyme A (EC 2.3.1.16; 2.3.1.9)
QEN71_RS01125
QEN71_RS02070
QEN71_RS14170
QEN71_RS15980
QEN71_RS18320
QEN71_RS18730
QEN71_RS21880
QEN71_RS22175
QEN71_RS22200
QEN71_RS22970
QEN71_RS27505
Butyrate--acetoacetate CoA-transferase (in reverse):
acetoacetyl-CoA + butanoate→acetoacetate + butanoyl-CoA (EC 2.8.3.9)
No genes
Butyrate--acetoacetate CoA-transferase (in reverse):
acetoacetyl-CoA + acetate→acetoacetate + acetyl-CoA (EC 2.8.3.9)
QEN71_RS06630
QEN71_RS17105
Alcohol dehydrogenase (in reverse):
acetaldehyde + NADH + H+→ethanol + NAD+ (EC 1.1.1.1)
QEN71_RS02555
QEN71_RS07550
QEN71_RS08075
QEN71_RS12765
QEN71_RS33145
QEN71_RS37215
QEN71_RS38175
3-hydroxyacyl-CoA dehydrogenase (in reverse):
acetoacetyl-CoA + NADH + H+→(S)-3-hydroxybutanoyl-CoA + NAD+ (EC 1.1.1.35)
QEN71_RS02065
QEN71_RS21890
QEN71_RS24020
QEN71_RS29945
QEN71_RS37855
Acetoacetate decarboxylase:
acetoacetate + H+→acetone + CO2 (EC 4.1.1.4)
QEN71_RS09075
QEN71_RS14990
(S)-3-hydroxybutanoyl-CoA→crotonyl-CoA + H2O (EC 4.2.1.150)
QEN71_RS01230
QEN71_RS02065
QEN71_RS02075
QEN71_RS04150
QEN71_RS06625
QEN71_RS08225
QEN71_RS10900
QEN71_RS15965
QEN71_RS16060
QEN71_RS19500
QEN71_RS21890
QEN71_RS22700
QEN71_RS26140
QEN71_RS27495
QEN71_RS29945
QEN71_RS30540
QEN71_RS30550
QEN71_RS30645
QEN71_RS33220
QEN71_RS35840
QEN71_RS38515
QEN71_RS39250
QEN71_RS39410
QEN71_RS39560
crotonyl-CoA[cytosol] + 2 NADH[cytosol] + 2 an oxidized ferredoxin [iron-sulfur] cluster[cytosol]→butanoyl-CoA[cytosol] + 2 NAD+[cytosol] + 2 a reduced ferredoxin [iron-sulfur] cluster[cytosol] (EC 1.3.1.109)
No genes
Butanal dehydrogenase (in reverse):
butanoyl-CoA + NAD(P)H + H+→1-butanal + coenzyme A + NAD(P)+ (EC 1.2.1.57)
No genes
Alcohol dehydrogenase (NADP(+)) (in reverse):
1-butanal + NADPH + H+→butan-1-ol + NADP+ (EC 1.1.1.2)
No genes
1-butanal + NADH + H+→butan-1-ol + NAD+
QEN71_RS37680

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information