MetaCyc Pathway: pyruvate fermentation to acetone in Paraburkholderia sabiae LMG 24235

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Pyruvate synthase:
pyruvate + coenzyme A + 2 an oxidized ferredoxin [iron-sulfur] cluster→acetyl-CoA + CO2 + H+ + 2 a reduced ferredoxin [iron-sulfur] cluster
(EC 1.2.7.1)
No genes
Acetyl-CoA C-acyltransferase:
2 acetyl-CoA→acetoacetyl-CoA + coenzyme A
(EC 2.3.1.16; 2.3.1.9)
QEN71_RS01125
QEN71_RS02070
QEN71_RS14170
QEN71_RS15980
QEN71_RS18320
QEN71_RS18730
QEN71_RS21880
QEN71_RS22175
QEN71_RS22200
QEN71_RS22970
QEN71_RS27505
Butyrate--acetoacetate CoA-transferase (in reverse):
acetoacetyl-CoA + butanoate→acetoacetate + butanoyl-CoA
(EC 2.8.3.9)
No genes
Butyrate--acetoacetate CoA-transferase (in reverse):
acetoacetyl-CoA + acetate→acetoacetate + acetyl-CoA
(EC 2.8.3.9)
QEN71_RS06630
QEN71_RS17105
Acetoacetate decarboxylase:
acetoacetate + H+→acetone + CO2
(EC 4.1.1.4)
QEN71_RS09075
QEN71_RS14990

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information