MetaCyc Pathway: 8-amino-7-oxononanoate biosynthesis I in Paraburkholderia sabiae LMG 24235

Add experiment(s):


a malonyl-[acp] + S-adenosyl-L-methionine→a malonyl-[acp] methyl ester + S-adenosyl-L-homocysteine (EC 2.1.1.197)
No genes
Beta-ketoacyl-acyl-carrier-protein synthase II:
a malonyl-[acp] + a malonyl-[acp] methyl ester + H+→a 3-oxoglutaryl-[acp] methyl ester + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.179; 2.3.1.41)
QEN71_RS03855
QEN71_RS03870
QEN71_RS03875
QEN71_RS04565
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
a 3-oxoglutaryl-[acp] methyl ester + NADPH + H+→a (3R)-3-hydroxyglutaryl-[acp] methyl ester + NADP+ (EC 1.1.1.100)
QEN71_RS01840
QEN71_RS02665
QEN71_RS02810
QEN71_RS03865
QEN71_RS04555
QEN71_RS07495
QEN71_RS08210
QEN71_RS08280
QEN71_RS10120
QEN71_RS11605
QEN71_RS12650
QEN71_RS12790
QEN71_RS13180
QEN71_RS15615
QEN71_RS15890
QEN71_RS15970
QEN71_RS16910
QEN71_RS16930
QEN71_RS18940
QEN71_RS19320
QEN71_RS19875
QEN71_RS22470
QEN71_RS22960
QEN71_RS24385
QEN71_RS24930
QEN71_RS25895
QEN71_RS27100
QEN71_RS29765
QEN71_RS30005
QEN71_RS30200
QEN71_RS30445
QEN71_RS31020
QEN71_RS31395
QEN71_RS32355
QEN71_RS32915
QEN71_RS33390
QEN71_RS33420
QEN71_RS33735
QEN71_RS33860
QEN71_RS34325
QEN71_RS34445
QEN71_RS35630
QEN71_RS36135
QEN71_RS36540
QEN71_RS36910
QEN71_RS37725
QEN71_RS38560
QEN71_RS38920
QEN71_RS39090
QEN71_RS39175
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R)-3-hydroxyglutaryl-[acp] methyl ester→a (2E)-enoylglutaryl-[acp] methyl ester + H2O (EC 4.2.1.59)
QEN71_RS06475
Enoyl-[acyl-carrier-protein] reductase (NADH) (in reverse):
a (2E)-enoylglutaryl-[acp] methyl ester + NADH + H+→a glutaryl-[acp] methyl ester + NAD+ (EC 1.3.1.9)
QEN71_RS06165
QEN71_RS13540
QEN71_RS30430
QEN71_RS30525
Beta-ketoacyl-acyl-carrier-protein synthase II:
a glutaryl-[acp] methyl ester + a malonyl-[acp] + H+→a 3-oxopimeloyl-[acp] methyl ester + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.179; 2.3.1.41)
QEN71_RS03855
QEN71_RS03870
QEN71_RS03875
QEN71_RS04565
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
a 3-oxopimeloyl-[acp] methyl ester + NADPH + H+→a (3R)-3-hydroxypimeloyl-[acp] methyl ester + NADP+ (EC 1.1.1.100)
QEN71_RS01840
QEN71_RS02665
QEN71_RS02810
QEN71_RS03865
QEN71_RS04555
QEN71_RS07495
QEN71_RS08210
QEN71_RS08280
QEN71_RS10120
QEN71_RS11605
QEN71_RS12650
QEN71_RS12790
QEN71_RS13180
QEN71_RS15615
QEN71_RS15890
QEN71_RS15970
QEN71_RS16910
QEN71_RS16930
QEN71_RS18940
QEN71_RS19320
QEN71_RS19875
QEN71_RS22470
QEN71_RS22960
QEN71_RS24385
QEN71_RS24930
QEN71_RS25895
QEN71_RS27100
QEN71_RS29765
QEN71_RS30005
QEN71_RS30200
QEN71_RS30445
QEN71_RS31020
QEN71_RS31395
QEN71_RS32355
QEN71_RS32915
QEN71_RS33390
QEN71_RS33420
QEN71_RS33735
QEN71_RS33860
QEN71_RS34325
QEN71_RS34445
QEN71_RS35630
QEN71_RS36135
QEN71_RS36540
QEN71_RS36910
QEN71_RS37725
QEN71_RS38560
QEN71_RS38920
QEN71_RS39090
QEN71_RS39175
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R)-3-hydroxypimeloyl-[acp] methyl ester→a (2E)-enoylpimeloyl-[acp] methyl ester + H2O (EC 4.2.1.59)
QEN71_RS06475
Enoyl-[acyl-carrier-protein] reductase (NADH) (in reverse):
a (2E)-enoylpimeloyl-[acp] methyl ester + NADH + H+→a pimeloyl-[acp] methyl ester + NAD+ (EC 1.3.1.9)
QEN71_RS06165
QEN71_RS13540
QEN71_RS30430
QEN71_RS30525
a pimeloyl-[acp] methyl ester + H2O→a pimeloyl-[acp] + methanol + H+ (EC 3.1.1.85)
No genes
8-amino-7-oxononanoate synthase:
a pimeloyl-[acp] + L-alanine + H+→(8S)-8-amino-7-oxononanoate + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.47)
QEN71_RS01095

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information