MetaCyc Pathway: benzoate biosynthesis III (CoA-dependent, non-β-oxidative) in Paraburkholderia sabiae LMG 24235

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Phenylalanine ammonia-lyase:
L-phenylalanine→trans-cinnamate + ammonium (EC 4.3.1.24; 4.3.1.25; 5.4.3.10)
No genes
trans-cinnamate + ATP + coenzyme A→(E)-cinnamoyl-CoA + AMP + diphosphate
No genes
Enoyl-CoA hydratase (in reverse):
(E)-cinnamoyl-CoA + H2O→(S)-3-hydroxy-3-phenylpropanoyl-CoA (EC 4.2.1.17)
QEN71_RS01230
QEN71_RS02065
QEN71_RS02075
QEN71_RS04150
QEN71_RS05365
QEN71_RS06625
QEN71_RS08225
QEN71_RS10900
QEN71_RS12380
QEN71_RS12385
QEN71_RS15965
QEN71_RS16060
QEN71_RS19420
QEN71_RS19500
QEN71_RS21890
QEN71_RS22700
QEN71_RS24020
QEN71_RS24025
QEN71_RS26140
QEN71_RS27495
QEN71_RS27510
QEN71_RS29945
QEN71_RS30540
QEN71_RS30550
QEN71_RS30645
QEN71_RS32940
QEN71_RS33220
QEN71_RS35840
QEN71_RS38515
QEN71_RS39250
QEN71_RS39410
QEN71_RS39560
(S)-3-hydroxy-3-phenylpropanoyl-CoA→benzaldehyde + acetyl-CoA
No genes
Benzaldehyde dehydrogenase (NAD(+)):
benzaldehyde + NAD+ + H2O→benzoate + NADH + 2 H+ (EC 1.2.1.28)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information