MetaCyc Pathway: L-histidine degradation II in Paraburkholderia sabiae LMG 24235

Histidine ammonia-lyase:
L-histidine→urocanate + ammonium (EC 4.3.1.3)

QEN71_RS03835

QEN71_RS07745

QEN71_RS23515

Urocanate hydratase (in reverse):
urocanate + H₂O→4-imidazolone-5-propanoate (EC 4.2.1.49)

QEN71_RS23505

Imidazolonepropionase:
4-imidazolone-5-propanoate + H₂O→N-formimino-L-glutamate (EC 3.5.2.7)

QEN71_RS23495

Formimidoylglutamate deiminase:
N-formimino-L-glutamate + H₂O→N-formyl-L-glutamate + ammonium (EC 3.5.3.13)

QEN71_RS23490

N-formylglutamate deformylase:
N-formyl-L-glutamate + H₂O→L-glutamate + formate (EC 3.5.1.68)

Links:

Pathway details at MetaCyc
Fitness data for 10 genes
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All MetaCyc pathways for Paraburkholderia sabiae LMG 24235

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information