MetaCyc Pathway: Entner-Doudoroff pathway II (non-phosphorylative) in Paraburkholderia sabiae LMG 24235

Add experiment(s):


Glucose 1-dehydrogenase (NADP(+)):
D-glucopyranose + NADP+→D-glucono-1,5-lactone + NADPH + H+ (EC 1.1.1.119; 1.1.1.360)
No genes
Gluconolactonase:
D-glucono-1,5-lactone + H2O→D-gluconate + H+ (spontaneous) (EC 3.1.1.17)
QEN71_RS13590
QEN71_RS18015
QEN71_RS18960
QEN71_RS38785
D-gluconate→2-dehydro-3-deoxy-D-gluconate + H2O (EC 4.2.1.140; 4.2.1.39)
QEN71_RS02295
QEN71_RS14610
QEN71_RS30680
QEN71_RS39295
2-dehydro-3-deoxy-D-gluconate→D-glyceraldehyde + pyruvate (EC 4.1.2.51)
No genes
D-glyceraldehyde + an oxidized electron carrier + H2O→D-glycerate + a reduced two electron carrier + H+ (EC 1.2.99.8)
QEN71_RS00050
QEN71_RS07095
QEN71_RS11040
QEN71_RS11670
QEN71_RS13660
QEN71_RS16945
QEN71_RS19510
QEN71_RS20195
QEN71_RS20440
QEN71_RS21070
QEN71_RS23580
QEN71_RS24925
QEN71_RS31880
QEN71_RS31965
QEN71_RS32565
QEN71_RS34295
QEN71_RS35780
QEN71_RS37085
QEN71_RS38180
QEN71_RS38780
QEN71_RS39635
QEN71_RS41285
QEN71_RS42030
D-glycerate + ATP→2-phospho-D-glycerate + ADP + H+ (EC 2.7.1.165)
QEN71_RS12190
Phosphopyruvate hydratase:
2-phospho-D-glycerate→phosphoenolpyruvate + H2O (EC 4.2.1.11)
QEN71_RS05880
QEN71_RS41510
Pyruvate kinase (in reverse):
phosphoenolpyruvate + ADP + H+→pyruvate + ATP (EC 2.7.1.40)
QEN71_RS02430
QEN71_RS12195
QEN71_RS41440
Pyruvate synthase:
pyruvate + coenzyme A + 2 an oxidized ferredoxin [iron-sulfur] cluster→acetyl-CoA + CO2 + H+ + 2 a reduced ferredoxin [iron-sulfur] cluster (EC 1.2.7.1)
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information