MetaCyc Pathway: superpathway of hexuronide and hexuronate degradation in Paraburkholderia sabiae LMG 24235

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Beta-glucuronidase:
a β-D-glucuronide + H2O→D-glucopyranuronate + an alcohol (EC 3.2.1.31)
No genes
Glucuronate isomerase:
aldehydo-D-galacturonate→D-tagaturonate (EC 5.3.1.12)
No genes
Tagaturonate reductase (in reverse):
D-tagaturonate + NADH + H+→D-altronate + NAD+ (EC 1.1.1.58)
QEN71_RS11435
D-glucopyranuronate→aldehydo-D-glucuronate (spontaneous)
No genes
Altronate dehydratase:
D-altronate→2-dehydro-3-deoxy-D-gluconate + H2O (EC 4.2.1.7)
QEN71_RS11450
QEN71_RS17240
QEN71_RS17245
QEN71_RS35705
Glucuronate isomerase:
aldehydo-D-glucuronate→D-fructuronate (EC 5.3.1.12)
No genes
Fructuronate reductase (in reverse):
D-fructuronate + NADH + H+→D-mannonate + NAD+ (EC 1.1.1.57)
No genes
Mannonate dehydratase:
D-mannonate→2-dehydro-3-deoxy-D-gluconate + H2O (EC 4.2.1.8)
No genes
2-dehydro-3-deoxy-D-gluconate + ATP→2-dehydro-3-deoxy-D-gluconate 6-phosphate + ADP + H+ (EC 2.7.1.178; 2.7.1.45)
QEN71_RS07255
QEN71_RS22180
QEN71_RS35755
2-dehydro-3-deoxy-phosphogluconate aldolase:
2-dehydro-3-deoxy-D-gluconate 6-phosphate→D-glyceraldehyde 3-phosphate + pyruvate (EC 4.1.2.14; 4.1.2.55)
QEN71_RS26915

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information