MetaCyc Pathway: catechol degradation to β-ketoadipate in Paraburkholderia sabiae LMG 24235

Catechol 1,2-dioxygenase: catechol + dioxygen→cis,cis-muconate + 2 H+ (EC 1.13.11.1)

QEN71_RS15715

QEN71_RS38170

Muconate cycloisomerase (in reverse): cis,cis-muconate + H+→(+)-muconolactone (EC 5.5.1.1)

QEN71_RS15720

Muconolactone Delta-isomerase: (+)-muconolactone→(4,5-dihydro-5-oxofuran-2-yl)-acetate (EC 5.3.3.4)

QEN71_RS15710

3-oxoadipate enol-lactonase: (4,5-dihydro-5-oxofuran-2-yl)-acetate + H2O→3-oxoadipate + H+ (EC 3.1.1.24)

QEN71_RS01205

QEN71_RS11655

QEN71_RS16920

QEN71_RS18110

QEN71_RS19560

QEN71_RS32550

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information