MetaCyc Pathway: NAD de novo biosynthesis III in Pontibacter actiniarum KMM 6156, DSM 19842

Add experiment(s):


Aspartate dehydrogenase:
L-aspartate + NAD(P)+→2-iminosuccinate + NAD(P)H + 2 H+ (EC 1.4.1.21)
No genes
Quinolinate synthase:
2-iminosuccinate + glycerone phosphate→quinolinate + phosphate + 2 H2O (EC 2.5.1.72)
No genes
Nicotinate-nucleotide diphosphorylase (carboxylating) (in reverse):
quinolinate + 2 H+ + 5-phospho-α-D-ribose 1-diphosphate→β-nicotinate D-ribonucleotide + CO2 + diphosphate (EC 2.4.2.19)
CA264_16940
Nicotinate-nucleotide adenylyltransferase:
β-nicotinate D-ribonucleotide + ATP + H+→nicotinate adenine dinucleotide + diphosphate (EC 2.7.7.18)
CA264_19230
NAD(+) synthase (glutamine-hydrolyzing):
nicotinate adenine dinucleotide + ATP + L-glutamine + H2O→NAD+ + AMP + L-glutamate + diphosphate + H+ (EC 6.3.5.1)
CA264_00760
NAD(+) synthase:
nicotinate adenine dinucleotide + ammonium + ATP→NAD+ + AMP + diphosphate + H+ (EC 6.3.1.5)
CA264_00760

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information