MetaCyc Pathway: superpathway of L-cysteine biosynthesis (fungi) in Pontibacter actiniarum KMM 6156, DSM 19842

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Homoserine O-acetyltransferase:
L-homoserine + acetyl-CoAO-acetyl-L-homoserine + coenzyme A
(EC 2.3.1.31)
CA264_02375
O-acetylhomoserine aminocarboxypropyltransferase:
O-acetyl-L-homoserine + hydrogen sulfide→L-homocysteine + acetate + H+
(EC 2.5.1.49)
CA264_02370
CA264_02530
Cystathionine beta-synthase:
L-homocysteine + L-serine→L-cystathionine + H2O
(EC 4.2.1.22)
CA264_13755
Cystathionine gamma-lyase:
L-cystathionine + H2O→L-cysteine + 2-oxobutanoate + ammonium
(EC 4.4.1.1)
CA264_00630
CA264_17730
CA264_20315
Cystathionine gamma-synthase:
L-cysteine + O-succinyl-L-homoserine→L-cystathionine + H+ + succinate
(EC 2.5.1.48)
CA264_00630
CA264_02370
CA264_02530
CA264_17730
Cysteine-S-conjugate beta-lyase:
L-cystathionine + H2O→L-homocysteine + ammonium + pyruvate
(EC 4.4.1.13)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information