MetaCyc Pathway: L-tyrosine degradation III in Hydrogenophaga sp. GW460-11-11-14-LB1

Add experiment(s):


Phenylalanine(histidine) transaminase:
L-tyrosine + pyruvate→3-(4-hydroxyphenyl)pyruvate + L-alanine
(EC 2.6.1.58)
No genes
Aspartate transaminase:
L-tyrosine + 2-oxoglutarate→3-(4-hydroxyphenyl)pyruvate + L-glutamate
(EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)
GFF1313
GFF1493
GFF1749
GFF2040
GFF3675
GFF3934
GFF4006
GFF4304
GFF4777
GFF4839
GFF5171
GFF5390
4-hydroxyphenylpyruvate decarboxylase:
3-(4-hydroxyphenyl)pyruvate + H+→(4-hydroxyphenyl)acetaldehyde + CO2
(EC 4.1.1.80)
No genes
Alcohol dehydrogenase (in reverse):
(4-hydroxyphenyl)acetaldehyde + NADH + H+→4-tyrosol + NAD+
(EC 1.1.1.1)
GFF2166
GFF3318
GFF3549
GFF4409
GFF4656
GFF5004
GFF5778
GFF5851

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information