MetaCyc Pathway: polyhydroxybutanoate biosynthesis in Hydrogenophaga sp. GW460-11-11-14-LB1

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Acetyl-CoA C-acyltransferase:
2 acetyl-CoA→acetoacetyl-CoA + coenzyme A (EC 2.3.1.16; 2.3.1.9)
GFF1723
GFF2108
GFF3471
GFF3554
GFF3722
GFF3782
GFF3813
GFF415
GFF429
GFF437
GFF4593
GFF4796
GFF4825
GFF5621
GFF5633
GFF5665
GFF5843
GFF678
GFF876
GFF906
Acetoacetyl-CoA reductase (in reverse):
acetoacetyl-CoA + NADPH + H+→(3R)-3-hydroxybutanoyl-CoA + NADP+ (EC 1.1.1.36)
GFF4795
(3R)-3-hydroxybutanoyl-CoA + poly-[(R)-3-hydroxybutanoate]→poly-[(R)-3-hydroxybutanoate] + coenzyme A (EC 2.3.1.304)
GFF281
GFF4797

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information