MetaCyc Pathway: ophthalmate biosynthesis in Hydrogenophaga sp. GW460-11-11-14-LB1

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2-oxobutanoate + L-glutamate→(S)-2-aminobutanoate + 2-oxoglutarate
No genes
Glutamate--cysteine ligase:
(S)-2-aminobutanoate + ATP + L-glutamate→γ-L-glutamyl-(S)-2-aminobutanoate + ADP + H+ + phosphate (EC 6.3.2.2)
GFF2645
GFF3561
Glutathione synthase:
γ-L-glutamyl-(S)-2-aminobutanoate + ATP + glycine→ophthalmate + ADP + H+ + phosphate (EC 6.3.2.3)
GFF2650

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information