MetaCyc Pathway: C4 photosynthetic carbon assimilation cycle, PEPCK type in Hydrogenophaga sp. GW460-11-11-14-LB1

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Carbonate dehydratase (in reverse):
CO2 + H2O→hydrogen carbonate + H+
(EC 4.2.1.1)
GFF1724
GFF5831
GFF914
Phosphoenolpyruvate carboxylase (in reverse):
hydrogen carbonate + phosphoenolpyruvate→oxaloacetate + phosphate
(EC 4.1.1.31)
GFF115
Aspartate transaminase (in reverse):
oxaloacetate + L-glutamate→L-aspartate + 2-oxoglutarate
(EC 2.6.1.1)
GFF1749
GFF2040
GFF3675
GFF3934
GFF4304
GFF4777
GFF4839
GFF5171
GFF5390
Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)) (in reverse):
oxaloacetate + NADPH + H+→(S)-malate + NADP+
(EC 1.1.1.40; 1.1.1.82)
GFF2469
GFF3306
L-aspartate[in]→L-aspartate[out]
No genes
(S)-malate[in]→(S)-malate[out]
No genes
Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)):
(S)-malate + NADP+→CO2 + pyruvate + NADPH
(EC 1.1.1.40)
GFF2469
GFF3306
Aspartate transaminase:
L-aspartate + 2-oxoglutarate→oxaloacetate + L-glutamate
(EC 2.6.1.1)
GFF1749
GFF2040
GFF3675
GFF3934
GFF4304
GFF4777
GFF4839
GFF5171
GFF5390
Alanine transaminase (in reverse):
pyruvate + L-glutamate→L-alanine + 2-oxoglutarate
(EC 2.6.1.2)
GFF3934
Phosphoenolpyruvate carboxykinase (ATP):
oxaloacetate + ATP→CO2 + phosphoenolpyruvate + ADP
(EC 4.1.1.49)
No genes
L-alanine[in]→L-alanine[out]
No genes
phosphoenolpyruvate[in]→phosphoenolpyruvate[out]
No genes
Alanine transaminase (in reverse):
L-alanine + 2-oxoglutarate→pyruvate + L-glutamate
(EC 2.6.1.2)
GFF3934
Pyruvate, phosphate dikinase:
pyruvate + ATP + phosphate→phosphoenolpyruvate + AMP + diphosphate + H+
(EC 2.7.9.1)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information