MetaCyc Pathway: mevalonate degradation in Hydrogenophaga sp. GW460-11-11-14-LB1

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Hydroxymethylglutaryl-CoA reductase:
(R)-mevalonate + coenzyme A + 2 NAD+→(S)-3-hydroxy-3-methylglutaryl-CoA + 2 NADH + 2 H+ (EC 1.1.1.88)
No genes
Hydroxymethylglutaryl-CoA lyase:
(S)-3-hydroxy-3-methylglutaryl-CoA→acetoacetate + acetyl-CoA (EC 4.1.3.4)
GFF1709
GFF3043
GFF3044
GFF3083
GFF3084
GFF982

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information