MetaCyc Pathway: propanoyl CoA degradation I in Hydrogenophaga sp. GW460-11-11-14-LB1

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Propionyl-CoA carboxylase:
propanoyl-CoA + ATP + hydrogen carbonate→(S)-methylmalonyl-CoA + ADP + H+ + phosphate
(EC 6.4.1.3)
GFF3353
GFF4785
GFF4786
GFF5139
GFF922
GFF944
GFF980
GFF985
Methylmalonyl-CoA epimerase (in reverse):
(S)-methylmalonyl-CoA→(R)-methylmalonyl-CoA
(EC 5.1.99.1)
GFF4783
Methylmalonyl-CoA mutase:
(R)-methylmalonyl-CoA→succinyl-CoA
(EC 5.4.99.2)
GFF1145
GFF1146
GFF2968
GFF2969
GFF385
GFF4788

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information