MetaCyc Pathway: gallate degradation III (anaerobic) in Hydrogenophaga sp. GW460-11-11-14-LB1

Add experiment(s):


Gallate decarboxylase:
gallate + H+→pyrogallol + CO2 (EC 4.1.1.59)
No genes
Pyrogallol hydroxytransferase:
pyrogallol + 1,2,3,5-tetrahydroxybenzene→phloroglucinol + 1,2,3,5-tetrahydroxybenzene (EC 1.97.1.2)
No genes
Phloroglucinol reductase (in reverse):
phloroglucinol + NADPH + H+→dihydrophloroglucinol + NADP+ (EC 1.3.1.57)
No genes
dihydrophloroglucinol + H2O→3-hydroxy-5-oxohexanoate + H+
No genes
Acetate CoA-transferase (in reverse):
3-hydroxy-5-oxohexanoate + acetyl-CoA→acetate + 3-hydroxy-5-oxohexanoyl-CoA (EC 2.8.3.8)
No genes
3-hydroxy-5-oxohexanoyl-CoA + coenzyme A→acetyl-CoA + (S)-3-hydroxybutanoyl-CoA
No genes
(S)-3-hydroxybutanoyl-CoA→crotonyl-CoA + H2O (EC 4.2.1.150)
GFF1003
GFF1566
GFF2070
GFF2072
GFF2109
GFF2111
GFF238
GFF2746
GFF2842
GFF2897
GFF2983
GFF3034
GFF3054
GFF3395
GFF3472
GFF3784
GFF4130
GFF414
GFF418
GFF4348
GFF435
GFF436
GFF4405
GFF4416
GFF4496
GFF4592
GFF4819
GFF482
GFF513
GFF5528
GFF5614
GFF5622
GFF5663
GFF5664
GFF5669
GFF5848
GFF5853
GFF5854
GFF619
GFF620
GFF726
GFF882
GFF915
GFF918
GFF931
GFF969
GFF979
crotonyl-CoA[cytosol] + 2 NADH[cytosol] + 2 an oxidized ferredoxin [iron-sulfur] cluster[cytosol]→butanoyl-CoA[cytosol] + 2 NAD+[cytosol] + 2 a reduced ferredoxin [iron-sulfur] cluster[cytosol] (EC 1.3.1.109)
No genes
Propionate CoA-transferase:
acetate + butanoyl-CoA→acetyl-CoA + butanoate (EC 2.8.3.1; 2.8.3.8)
No genes
Phosphate acetyltransferase:
acetyl-CoA + phosphate→acetyl phosphate + coenzyme A (EC 2.3.1.8)
GFF4710
Acetate kinase (in reverse):
acetyl phosphate + ADP→acetate + ATP (EC 2.7.2.1; 2.7.2.15)
GFF363
GFF4711

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information