MetaCyc Pathway: superpathway of adenosine nucleotides de novo biosynthesis I in Pectobacterium carotovorum WPP14

Add experiment(s):


Adenylosuccinate synthase:
IMP + L-aspartate + GTP→adenylosuccinate + GDP + 2 H+ + phosphate (EC 6.3.4.4)
HER17_RS02610
Adenylosuccinate lyase:
adenylosuccinate→AMP + fumarate (EC 4.3.2.2)
HER17_RS01230
HER17_RS11635
Adenylate kinase:
AMP + ATP→2 ADP (EC 2.7.4.3)
HER17_RS15685
Ribonucleoside-diphosphate reductase (in reverse):
ADP + a reduced thioredoxin→dADP + an oxidized thioredoxin + H2O (EC 1.17.4.1)
HER17_RS05480
HER17_RS05485
HER17_RS05490
HER17_RS15595
HER17_RS15600
Nucleoside-diphosphate kinase:
dADP + ATP→ADP + dATP (EC 2.7.4.6)
HER17_RS06080

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information