| ATP + NAD+→3'-dehydro-ATP + NADH + H+ |
| No genes |
| 3'-dehydro-ATP→3'-amino-3'-deoxyATP |
| No genes |
| 3'-amino-3'-deoxyATP + H2O→3'-amino-3'-deoxy-AMP + diphosphate + H+ |
| No genes |
| 3'-amino-3'-deoxy-AMP + H2O→3'-amino-3'-deoxyadenosine + phosphate |
| No genes |
| 3'-amino-3'-deoxyadenosine + L-tyrosine→N6,N6,O-tridemethylpuromycin + H2O |
| No genes |
| N6,N6,O-tridemethylpuromycin + acetyl-CoA→N-acetyl-N6,N6,O-tridemethylpuromycin + coenzyme A + H+ |
| No genes |
| N-acetyl-N6,N6,O-tridemethylpuromycin + S-adenosyl-L-methionine→N-acetyl-N6,O-didemethylpuromycin + S-adenosyl-L-homocysteine + H+ |
| No genes |
| N-acetyl-N6,O-didemethylpuromycin + S-adenosyl-L-methionine→N-acetyl-O-demethylpuromycin + S-adenosyl-L-homocysteine + H+ |
| No genes |
O-demethylpuromycin O-methyltransferase:
N-acetyl-O-demethylpuromycin + S-adenosyl-L-methionine→N-acetylpuromycin + S-adenosyl-L-homocysteine + H+ (EC 2.1.1.38) |
| HER17_RS09830 |
| N-acetylpuromycin + H2O→puromycin + acetate |
| No genes |
Links:
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information