MetaCyc Pathway: superpathway of L-phenylalanine biosynthesis in Pantoea agglomerans CFBP13505 P0401

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3-deoxy-7-phosphoheptulonate synthase:
D-erythrose 4-phosphate + phosphoenolpyruvate + H2O→3-deoxy-D-arabino-heptulosonate 7-phosphate + phosphate (EC 2.5.1.54)
PagCFBP13516_RS04770
PagCFBP13516_RS11085
PagCFBP13516_RS13720 (aroG)
3-dehydroquinate synthase:
3-deoxy-D-arabino-heptulosonate 7-phosphate→3-dehydroquinate + phosphate (EC 4.2.3.4)
PagCFBP13516_RS01895 (aroB)
3-dehydroquinate dehydratase:
3-dehydroquinate→3-dehydroshikimate + H2O (EC 4.2.1.10)
PagCFBP13516_RS02430 (aroQ)
PagCFBP13516_RS04405 (eno)
Shikimate dehydrogenase (in reverse):
3-dehydroshikimate + NADPH + H+→shikimate + NADP+ (EC 1.1.1.25)
PagCFBP13516_RS02330 (aroE)
Shikimate kinase:
shikimate + ATP→shikimate 3-phosphate + ADP + H+ (EC 2.7.1.71)
PagCFBP13516_RS01890 (aroK)
PagCFBP13516_RS15225 (aroL)
3-phosphoshikimate 1-carboxyvinyltransferase:
shikimate 3-phosphate + phosphoenolpyruvate→5-enolpyruvoyl-shikimate 3-phosphate + phosphate (EC 2.5.1.19)
PagCFBP13516_RS12945 (aroA)
Chorismate synthase:
5-enolpyruvoyl-shikimate 3-phosphate→chorismate + phosphate (EC 4.2.3.5)
PagCFBP13516_RS06340 (aroC)
Chorismate mutase:
chorismate→prephenate (EC 5.4.99.5)
PagCFBP13516_RS04775 (tyrA)
PagCFBP13516_RS04780 (pheA)
PagCFBP13516_RS22735
Prephenate dehydratase:
prephenate + H+→3-phenyl-2-oxopropanoate + CO2 + H2O (EC 4.2.1.51)
PagCFBP13516_RS03420
PagCFBP13516_RS04780 (pheA)
Aspartate transaminase (in reverse):
3-phenyl-2-oxopropanoate + L-glutamate→L-phenylalanine + 2-oxoglutarate (EC 2.6.1.1; 2.6.1.27; 2.6.1.57)
PagCFBP13516_RS00080
PagCFBP13516_RS01025
PagCFBP13516_RS01090
PagCFBP13516_RS01115 (pdxR)
PagCFBP13516_RS03520
PagCFBP13516_RS03525
PagCFBP13516_RS06375 (pdxR)
PagCFBP13516_RS06560
PagCFBP13516_RS07470 (hisC)
PagCFBP13516_RS09780
PagCFBP13516_RS12850
PagCFBP13516_RS14200
PagCFBP13516_RS18070
PagCFBP13516_RS18340
PagCFBP13516_RS23715

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information