MetaCyc Pathway: vibriobactin biosynthesis in Pantoea agglomerans CFBP13505 P0401

Add experiment(s):


Isochorismate synthase:
chorismate→isochorismate
(EC 5.4.4.2)
PagCFBP13516_RS17355
Isochorismatase:
isochorismate + H2O→(2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate + pyruvate
(EC 3.3.2.1)
PagCFBP13516_RS07860 (biuH)
PagCFBP13516_RS10425
PagCFBP13516_RS17365
PagCFBP13516_RS18040
PagCFBP13516_RS21070
PagCFBP13516_RS22205
PagCFBP13516_RS22885
2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase:
(2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate + NAD+→2,3-dihydroxybenzoate + NADH + H+
(EC 1.3.1.28)
PagCFBP13516_RS17370 (dhbA)
2,3-dihydroxybenzoate + ATP + H+→(2,3-dihydroxybenzoyl)adenylate + diphosphate (EC 6.2.1.71)
PagCFBP13516_RS17360
(2,3-dihydroxybenzoyl)adenylate + a holo-[VibB aryl-carrier protein]→a 2,3-dihydroxybenzoyl-[VibB] + AMP + H+ (EC 6.2.1.71)
No genes
a 2,3-dihydroxybenzoyl-[VibB] + ATP + L-threonine + a VibF non-ribosomal peptide synthetase→a dihydroxyphenyl-5-methyloxazoline-[VibF] + AMP + diphosphate + H+ + H2O + a holo-[VibB aryl-carrier protein]
No genes
a 2,3-dihydroxybenzoyl-[VibB] + norspermidine→norspermidine-2,3-dihydroxybenzoate + H+ + a holo-[VibB aryl-carrier protein]
No genes
a dihydroxyphenyl-5-methyloxazoline-[VibF] + norspermidine-2,3-dihydroxybenzoate→dihydroxyphenyl-5-methyloxazoline-norspermidine-2,3-dihydroxybenzoate + 2 H+ + a VibF non-ribosomal peptide synthetase
No genes
a dihydroxyphenyl-5-methyloxazoline-[VibF] + dihydroxyphenyl-5-methyloxazoline-norspermidine-2,3-dihydroxybenzoate→vibriobactin + a VibF non-ribosomal peptide synthetase
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information