MetaCyc Pathway: superpathway of adenosine nucleotides de novo biosynthesis II in Pantoea agglomerans CFBP13505 P0401

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Adenylosuccinate synthase:
IMP + L-aspartate + GTP→adenylosuccinate + GDP + 2 H+ + phosphate (EC 6.3.4.4)
PagCFBP13516_RS02630
Adenylosuccinate lyase:
adenylosuccinate→AMP + fumarate (EC 4.3.2.2)
PagCFBP13516_RS11980 (purB)
Adenylate kinase:
AMP + ATP→2 ADP (EC 2.7.4.3)
PagCFBP13516_RS14695 (adk)
Ribonucleoside-diphosphate reductase (in reverse):
ADP + a reduced thioredoxin→dADP + an oxidized thioredoxin + H2O (EC 1.17.4.1)
PagCFBP13516_RS04910 (nrdF)
PagCFBP13516_RS04915 (nrdE)
PagCFBP13516_RS04920 (nrdI)
PagCFBP13516_RS06660 (nrdB)
PagCFBP13516_RS06665 (nrdA)
Ribonucleoside-diphosphate reductase (in reverse):
ADP + a reduced NrdH glutaredoxin-like protein→dADP + an oxidized NrdH glutaredoxin-like protein + H2O (EC 1.17.4.1)
PagCFBP13516_RS04910 (nrdF)
PagCFBP13516_RS04915 (nrdE)
PagCFBP13516_RS06660 (nrdB)
PagCFBP13516_RS06665 (nrdA)
Nucleoside-diphosphate kinase:
dADP + ATP→ADP + dATP (EC 2.7.4.6)
PagCFBP13516_RS05325 (ndk)
ATP + formate + H+→dATP + CO2 + H2O (EC 1.1.98.6)
PagCFBP13516_RS17145 (nrdD)

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information