MetaCyc Pathway: 2-allylmalonyl-CoA biosynthesis in Serratia liquefaciens MT49

Add experiment(s):


propanoyl-CoA + TcsB polyketide synthase→propanoyl-[TcsB polyketide synthase] + coenzyme A
No genes
malonyl-CoA + TcsA polyketide synthase→malonyl-[TcsA polyketide synthase] + coenzyme A
No genes
malonyl-[TcsA polyketide synthase] + propanoyl-[TcsB polyketide synthase] + H+→3-oxopentanoyl-[TcsA polyketide synthase] + CO2 + TcsB polyketide synthase
No genes
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
3-oxopentanoyl-[TcsA polyketide synthase] + NADPH + H+→(3R)-3-hydroxypentanoyl-[TcsA polyketide synthase] + NADP+ (EC 1.1.1.100)
IAI46_00395
IAI46_02715
IAI46_02810
IAI46_03145
IAI46_04100
IAI46_05430
IAI46_05725
IAI46_07125
IAI46_09790
IAI46_10535
IAI46_12450
IAI46_17490
IAI46_19920
IAI46_21070
IAI46_22865
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
(3R)-3-hydroxypentanoyl-[TcsA polyketide synthase]→(2E)-pent-2-enoyl-[TcsA polyketide synthase] + H2O (EC 4.2.1.59)
IAI46_08860
IAI46_12205
IAI46_20205
(2E)-pent-2-enoyl-[TcsA polyketide synthase] + CO2 + NADPH→2-carboxypentanoyl-[TcsA polyketide synthase] + NADP+
No genes
2-carboxypentanoyl-[TcsA polyketide synthase] + FAD + H+→2-allylmalonyl-[TcsA polyketide synthase] + FADH2
No genes
2-allylmalonyl-[TcsA polyketide synthase] + coenzyme A→2-allylmalonyl-CoA + TcsA polyketide synthase
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information