MetaCyc Pathway: 8-amino-7-oxononanoate biosynthesis IV in Serratia liquefaciens MT49

Add experiment(s):


glutaryl-CoA + a malonyl-[acp] + H+→a 3-oxopimeloyl-[acp] + CO2 + coenzyme A
No genes
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
a 3-oxopimeloyl-[acp] + NADPH + H+→a (3R)-3-hydroxypimeloyl-[acp] + NADP+
(EC 1.1.1.100)
IAI46_00395
IAI46_02715
IAI46_02810
IAI46_03145
IAI46_04100
IAI46_05430
IAI46_05725
IAI46_07125
IAI46_09790
IAI46_10535
IAI46_12450
IAI46_17490
IAI46_19920
IAI46_21070
IAI46_22865
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R)-3-hydroxypimeloyl-[acp]→a 2-enoyl-pimeloyl-[acp] + H2O
(EC 4.2.1.59)
IAI46_08860
IAI46_12205
IAI46_20205
Enoyl-[acyl-carrier-protein] reductase (NADH) (in reverse):
a 2-enoyl-pimeloyl-[acp] + NADH + H+→a pimeloyl-[acp] + NAD+
(EC 1.3.1.9)
No genes
8-amino-7-oxononanoate synthase:
a pimeloyl-[acp] + L-alanine + H+→(8S)-8-amino-7-oxononanoate + a soluble [acyl-carrier protein] + CO2
(EC 2.3.1.47)
IAI46_06530
IAI46_16540

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information