MetaCyc Pathway: siroheme biosynthesis in Serratia liquefaciens MT49

Add experiment(s):


Uroporphyrinogen-III C-methyltransferase:
uroporphyrinogen-III + S-adenosyl-L-methionine→precorrin-1 + S-adenosyl-L-homocysteine + H+ (EC 2.1.1.107)
IAI46_01720
IAI46_03710
IAI46_23670
Uroporphyrinogen-III C-methyltransferase:
precorrin-1 + S-adenosyl-L-methionine→precorrin-2 + S-adenosyl-L-homocysteine (EC 2.1.1.107)
IAI46_01720
IAI46_03710
IAI46_23670
Precorrin-2 dehydrogenase:
precorrin-2 + NAD+→sirohydrochlorin + NADH + 2 H+ (EC 1.3.1.76)
IAI46_03710
IAI46_23670
Sirohydrochlorin ferrochelatase:
sirohydrochlorin + Fe2+→siroheme + 2 H+ (EC 4.99.1.4)
IAI46_03710
IAI46_23670

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information