MetaCyc Pathway: superpathway of hexitol degradation (bacteria) in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

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Mannitol-1-phosphate 5-dehydrogenase:
D-mannitol 1-phosphate + NAD+→β-D-fructofuranose 6-phosphate + NADH + H+ (EC 1.1.1.17)
GFF417
Sorbitol-6-phosphate 2-dehydrogenase:
D-sorbitol 6-phosphate + NAD+→keto-D-fructose 6-phosphate + NADH + H+ (EC 1.1.1.140)
GFF4699
galactitol[out] + an [HPr protein]-Nπ-phospho-L-histidine[in]→galactitol 1-phosphate[in] + an [HPr]-L-histidine[in] (EC 2.7.1.200)
GFF1524
GFF1525
GFF1526
Galactitol-1-phosphate 5-dehydrogenase:
galactitol 1-phosphate + NAD+→keto-D-tagatose 6-phosphate + NADH + H+ (EC 1.1.1.251)
GFF1523
6-phosphofructokinase:
β-D-fructofuranose 6-phosphate + ATP→β-D-fructofuranose 1,6-bisphosphate + ADP + H+ (EC 2.7.1.11)
GFF2283
GFF3516
Fructose-bisphosphate aldolase:
β-D-fructofuranose 1,6-bisphosphate→glycerone phosphate + D-glyceraldehyde 3-phosphate (EC 4.1.2.13)
GFF3020
GFF314
GFF3839
Fructose-bisphosphatase:
β-D-fructofuranose 1,6-bisphosphate + H2O→β-D-fructofuranose 6-phosphate + phosphate (EC 3.1.3.11)
GFF2306
GFF660
GFF880
keto-D-tagatose 6-phosphate→D-tagatofuranose 6-phosphate (spontaneous)
No genes
Tagatose-6-phosphate kinase:
D-tagatofuranose 6-phosphate + ATP→D-tagatofuranose 1,6-bisphosphate + ADP + H+ (EC 2.7.1.144)
GFF1527
GFF2283
GFF3516
GFF3772
Triose-phosphate isomerase (in reverse):
glycerone phosphate→D-glyceraldehyde 3-phosphate (EC 5.3.1.1)
GFF2302
GFF902
Tagatose-bisphosphate aldolase:
D-tagatofuranose 1,6-bisphosphate→glycerone phosphate + D-glyceraldehyde 3-phosphate (EC 4.1.2.40)
GFF1527
GFF1531
GFF314
Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating):
D-glyceraldehyde 3-phosphate + NAD+ + phosphate→3-phospho-D-glyceroyl phosphate + NADH + H+ (EC 1.2.1.12)
GFF3478
Phosphoglycerate kinase (in reverse):
3-phospho-D-glyceroyl phosphate + ADP→3-phospho-D-glycerate + ATP (EC 2.7.2.3)
GFF3021
3-phospho-D-glycerate→2-phospho-D-glycerate (EC 5.4.2.12)
GFF1063
GFF398
GFF648
3-phospho-D-glycerate→2-phospho-D-glycerate (EC 5.4.2.11)
GFF648
Phosphopyruvate hydratase:
2-phospho-D-glycerate→phosphoenolpyruvate + H2O (EC 4.2.1.11)
GFF4832
Pyruvate kinase (in reverse):
phosphoenolpyruvate + ADP + H+→pyruvate + ATP (EC 2.7.1.40)
GFF1633
GFF3567
GFF3582
Pyruvate, water dikinase:
pyruvate + ATP + H2O→phosphoenolpyruvate + AMP + 2 H+ + phosphate (EC 2.7.9.2)
GFF3539

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information