MetaCyc Pathway: chorismate biosynthesis I in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

3-deoxy-7-phosphoheptulonate synthase: D-erythrose 4-phosphate + phosphoenolpyruvate + H2O→3-deoxy-D-arabino-heptulosonate 7-phosphate + phosphate (EC 2.5.1.54)

GFF3536

GFF4176

GFF8

3-dehydroquinate synthase: 3-deoxy-D-arabino-heptulosonate 7-phosphate→3-dehydroquinate + phosphate (EC 4.2.3.4)

GFF630

3-dehydroquinate dehydratase: 3-dehydroquinate→3-dehydroshikimate + H2O (EC 4.2.1.10)

GFF3548

GFF4832

Shikimate dehydrogenase (in reverse): 3-dehydroshikimate + NADPH + H+→shikimate + NADP+ (EC 1.1.1.25)

GFF1732

GFF2397

GFF3549

Shikimate kinase: shikimate + ATP→shikimate 3-phosphate + ADP + H+ (EC 2.7.1.71)

GFF4286

GFF629

3-phosphoshikimate 1-carboxyvinyltransferase: shikimate 3-phosphate + phosphoenolpyruvate→5-enolpyruvoyl-shikimate 3-phosphate + phosphate (EC 2.5.1.19)

GFF3665

Chorismate synthase: 5-enolpyruvoyl-shikimate 3-phosphate→chorismate + phosphate (EC 4.2.3.5)

GFF1950

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information