MetaCyc Pathway: L-tyrosine biosynthesis I in Klebsiella pneumoniae MRSN742743

Add experiment(s):


Chorismate mutase:
chorismate→prephenate (EC 5.4.99.5)
KFA93_RS24595 (pheA;go_function=chorismate)
KFA93_RS24605 (tyrA;go_function=chorismate)
Prephenate dehydrogenase:
prephenate + NAD+→3-(4-hydroxyphenyl)pyruvate + CO2 + NADH (EC 1.3.1.12)
KFA93_RS24605 (tyrA;go_function=chorismate)
Aspartate transaminase (in reverse):
3-(4-hydroxyphenyl)pyruvate + L-glutamate→L-tyrosine + 2-oxoglutarate (EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)
KFA93_RS00820
KFA93_RS02730
KFA93_RS02735
KFA93_RS03475
KFA93_RS03560
KFA93_RS06075 (alaA;inference=COORDINATES)
KFA93_RS07095 (hisC;go_function=histidinol-phosphate)
KFA93_RS10485
KFA93_RS14220
KFA93_RS19085
KFA93_RS21720 (tyrB;inference=COORDINATES)
KFA93_RS23420
KFA93_RS23440

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information