MetaCyc Pathway: superpathway of fucose and rhamnose degradation in Klebsiella pneumoniae MRSN742743

Add experiment(s):


β-L-fucopyranose→α-L-fucopyranose (spontaneous) (EC 5.1.3.29)
KFA93_RS17435 (fucU;go_function=racemase)
α-L-rhamnopyranose→β-L-rhamnopyranose (EC 5.1.3.32)
KFA93_RS22630 (rhaM;go_component=cytoplasm|0005737||IEA;go_function=racemase)
L-fucose isomerase:
α-L-fucopyranose→L-fuculose (EC 5.3.1.25)
KFA93_RS17425 (fucI;go_component=cytoplasm|0005737||IEA;go_function=L-fucose)
L-rhamnose isomerase:
β-L-rhamnopyranose→keto-L-rhamnulose (EC 5.3.1.14)
KFA93_RS22665 (rhaA;go_function=L-rhamnose)
L-fuculokinase:
L-fuculose + ATP→L-fuculose 1-phosphate + ADP + H+ (EC 2.7.1.51)
KFA93_RS17430 (fucK;go_function=L-fuculokinase)
keto-L-rhamnulose→L-rhamnulofuranose (spontaneous)
No genes
L-fuculose-phosphate aldolase:
L-fuculose 1-phosphate→(S)-lactaldehyde + glycerone phosphate (EC 4.1.2.17)
KFA93_RS17415 (fucA;go_function=zinc)
Rhamnulokinase:
L-rhamnulofuranose + ATP→L-rhamnulose 1-phosphate + ADP + H+ (EC 2.7.1.5)
KFA93_RS22670 (rhaB;go_function=rhamnulokinase)
Rhamnulose-1-phosphate aldolase:
L-rhamnulose 1-phosphate→(S)-lactaldehyde + glycerone phosphate (EC 4.1.2.19)
KFA93_RS22660 (rhaD;inference=COORDINATES)
Lactaldehyde dehydrogenase:
(S)-lactaldehyde + NAD+ + H2O→(S)-lactate + NADH + 2 H+ (EC 1.2.1.22)
KFA93_RS04445 (gabD;go_function=succinate-semialdehyde)
KFA93_RS22200 (aldA;go_function=oxidoreductase)
KFA93_RS22635 (fucO;go_function=lactaldehyde)
Lactaldehyde reductase (in reverse):
(S)-lactaldehyde + NADH + H+→(S)-propane-1,2-diol + NAD+ (EC 1.1.1.77)
KFA93_RS17410 (fucO;go_function=oxidoreductase)
KFA93_RS22635 (fucO;go_function=lactaldehyde)
(S)-lactate[in] + an electron-transfer quinone→pyruvate[in] + an electron-transfer quinol (EC 1.1.5.M6)
KFA93_RS09285 (lldD;go_function=lactate)
KFA93_RS15550 (lldD;go_function=lactate)

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information