MetaCyc Pathway: L-tyrosine degradation III in Escherichia coli BW25113
| Phenylalanine(histidine) transaminase: L-tyrosine + pyruvate→3-(4-hydroxyphenyl)pyruvate + L-alanine (EC 2.6.1.58) |
| No genes |
| Aspartate transaminase: L-tyrosine + 2-oxoglutarate→3-(4-hydroxyphenyl)pyruvate + L-glutamate (EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57) |
| b0928 (aspC) |
| b2021 (hisC) |
| b4054 (tyrB) |
| b4340 (yjiR) |
| 4-hydroxyphenylpyruvate decarboxylase: 3-(4-hydroxyphenyl)pyruvate + H+→(4-hydroxyphenyl)acetaldehyde + CO2 (EC 4.1.1.80) |
| No genes |
| Alcohol dehydrogenase (in reverse): (4-hydroxyphenyl)acetaldehyde + NADH + H+→4-tyrosol + NAD+ (EC 1.1.1.1) |
| b0325 (yahK) |
| b0356 (frmA) |
| b1241 (adhE) |
| b1478 (adhP) |
| b3253 (yhdH) |
| b4269 (yjgB) |
| b3589 (yiaY) |
Links:
- Pathway details at MetaCyc
- Fitness data for 11 genes
- All MetaCyc pathways for Escherichia coli BW25113
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information