MetaCyc Pathway: uracil degradation III in Escherichia coli BW25113
| uracil + FMNH2 + NADH + dioxygen→(Z)-3-ureidoacrylate + FMN + NAD+ + H+ + H2O (EC 1.14.99.46) |
| b1012 (b1012) |
| (Z)-3-ureidoacrylate + H2O→carbamate + (Z)-3-aminoacrylate + H+ (EC 3.5.1.110) |
| b1011 (b1011) |
| carbamate + 2 H+→CO2 + ammonium (spontaneous) (EC 3.5.1.110; 3.5.1.20; 3.5.1.54; 4.2.1.104) |
| b0340 (cynS) |
| b0711 (ybgJ) |
| b0712 (ybgK) |
| (Z)-3-aminoacrylate + H+ + H2O→3-oxopropanoate + ammonium (spontaneous) |
| b1010 (ycdK) |
| 3-oxopropanoate + NADPH + H+→3-hydroxypropanoate + NADP+ (EC 1.1.1.298) |
| b1008 (ycdI) |
| b1539 (ydfG) |
Links:
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information