3-phenylpropanoate dioxygenase:
3-phenylpropanoate + NADH + dioxygen + H+→3-(5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate + NAD+ (EC 1.14.12.19) |
| b2538 (hcaE) |
| b2539 (hcaF) |
| b2540 (hcaC) |
| b2542 (hcaD) |
| 3-(3-hydroxyphenyl)propanoate + NADH + dioxygen + H+→3-(2,3-dihydroxyphenyl)propanoate + NAD+ + H2O (EC 1.14.13.127) |
| b0347 (mhpA) |
| 3-(5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate + NAD+→3-(2,3-dihydroxyphenyl)propanoate + NADH + H+ (EC 1.3.1.87) |
| b2541 (hcaB) |
3-carboxyethylcatechol 2,3-dioxygenase:
3-(2,3-dihydroxyphenyl)propanoate + dioxygen→(2Z,4E)-2-hydroxy-6-oxonona-2,4-diene-1,9-dioate + H+ (EC 1.13.11.16) |
| b0348 (mhpB) |
| (2Z,4E)-2-hydroxy-6-oxonona-2,4-diene-1,9-dioate + H2O→(2Z)-2-hydroxypenta-2,4-dienoate + H+ + succinate (EC 3.7.1.14) |
| b0349 (mhpC) |
2-oxopent-4-enoate hydratase (in reverse):
(2Z)-2-hydroxypenta-2,4-dienoate + H2O→(S)-4-hydroxy-2-oxopentanoate (EC 4.2.1.80) |
| b0350 (mhpD) |
4-hydroxy-2-oxovalerate aldolase:
(S)-4-hydroxy-2-oxopentanoate→acetaldehyde + pyruvate (EC 4.1.3.39) |
| b0352 (mhpE) |
Acetaldehyde dehydrogenase (acetylating):
acetaldehyde + coenzyme A + NAD+→acetyl-CoA + NADH + H+ (EC 1.2.1.10) |
| b0351 (mhpF) |
| b1241 (adhE) |
| b2455 (eutE) |
Links:
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information