MetaCyc Pathway: thiamine diphosphate salvage V in Escherichia coli BW25113

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Hydroxyethylthiazole kinase:
5-(2-hydroxyethyl)-4-methyl-1,3-thiazole-2-carboxylate + ATP→2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate + ADP + H+ (EC 2.7.1.50)
b2104 (thiM)
Thiamine-phosphate diphosphorylase:
2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2 H+→thiamine phosphate + CO2 + diphosphate (EC 2.5.1.3)
b3993 (thiE)
Thiamine-phosphate kinase:
thiamine phosphate + ATP→thiamine diphosphate + ADP (EC 2.7.4.16)
b0417 (thiL)

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information