MetaCyc Pathway: guanosine deoxyribonucleotides de novo biosynthesis II in Escherichia coli BW25113
| Ribonucleoside-diphosphate reductase (in reverse): GDP + a reduced thioredoxin→dGDP + an oxidized thioredoxin + H2O (EC 1.17.4.1) |
| b2234 (nrdA) |
| b2235 (nrdB) |
| b2674 (nrdI) |
| b2675 (nrdE) |
| b2676 (nrdF) |
| Ribonucleoside-diphosphate reductase (in reverse): GDP + a reduced NrdH glutaredoxin-like protein→dGDP + an oxidized NrdH glutaredoxin-like protein + H2O (EC 1.17.4.1) |
| b2234 (nrdA) |
| b2235 (nrdB) |
| b2675 (nrdE) |
| b2676 (nrdF) |
| Nucleoside-diphosphate kinase: dGDP + ATP→dGTP + ADP (EC 2.7.4.6) |
| b0474 (adk) |
| b2518 (ndk) |
| GTP + formate + H+→dGTP + CO2 + H2O (EC 1.1.98.6) |
| b4238 (nrdD) |
Links:
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information