MetaCyc Pathway: superpathway of pyrimidine ribonucleosides salvage in Escherichia coli BW25113
| Cytidine deaminase: cytidine + H+ + H2O→uridine + ammonium (EC 3.5.4.5) |
| b2143 (cdd) |
| cytidine + ATP→CMP + ADP + H+ (EC 2.7.1.213; 2.7.1.48) |
| b2066 (udk) |
| Cytidylate kinase: CMP + ATP→CDP + ADP (EC 2.7.4.14; 2.7.4.25) |
| b0910 (cmk) |
| Uridine nucleosidase: uridine + H2O→uracil + D-ribofuranose (EC 3.2.2.3) |
| b0030 (rihC) |
| b0651 (rihA) |
| b2162 (rihB) |
| Uridine kinase: uridine + ATP→UMP + ADP + H+ (EC 2.7.1.48) |
| b2066 (udk) |
| Nucleoside-diphosphate kinase: CDP + ATP→CTP + ADP (EC 2.7.4.6) |
| b0474 (adk) |
| b2518 (ndk) |
| Uracil phosphoribosyltransferase (in reverse): uracil + 5-phospho-α-D-ribose 1-diphosphate→UMP + diphosphate (EC 2.4.2.9) |
| b2498 (upp) |
| Cytidylate kinase: UMP + ATP→UDP + ADP (EC 2.7.4.14; 2.7.4.22) |
| b0171 (pyrH) |
| b0910 (cmk) |
| Nucleoside-diphosphate kinase: UDP + ATP→UTP + ADP (EC 2.7.4.6) |
| b0474 (adk) |
| b2518 (ndk) |
| CTP synthase: UTP + ATP + L-glutamine + H2O→CTP + ADP + L-glutamate + 2 H+ + phosphate (EC 6.3.4.2) |
| b2780 (pyrG) |
Links:
- Pathway details at MetaCyc
- Fitness data for 11 genes
- All MetaCyc pathways for Escherichia coli BW25113
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information