MetaCyc Pathway: superpathway of 2,3-butanediol biosynthesis in Escherichia coli BW25113

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Acetolactate synthase:
2 pyruvate + H+→(S)-2-acetolactate + CO2
(EC 2.2.1.6)
b0078 (ilvH)
b3670 (ilvN)
b3671 (ilvB)
b3769 (ilvM)
b0077 (ilvI)
(R)-acetoin + NADH + H+→(R,S)-2,3-butanediol + NAD+
No genes
(S)-2-acetolactate + an oxidized electron carrier + H+→CO2 + diacetyl + a reduced two electron carrier (spontaneous)
No genes
diacetyl + NADH + H+→(S)-acetoin + NAD+ (EC 1.1.1.304)
b2426 (ucpA)
(S)-acetoin + NADH + H+→(R,S)-2,3-butanediol + NAD+
No genes
(S,S)-butanediol dehydrogenase (in reverse):
(S)-acetoin + NADH + H+→(S,S)-2,3-butanediol + NAD+
(EC 1.1.1.76)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information