MetaCyc Pathway: purine nucleotides degradation II (aerobic) in Escherichia coli BW25113

Add experiment(s):


5'-nucleotidase:
AMP + H2O→adenosine + phosphate (EC 3.1.3.5)
b0383 (phoA)
b0480 (ushA)
b2291 (yfbR)
b2744 (surE)
b4055 (aphA)
b4374 (yjjG)
IMP dehydrogenase:
IMP + NAD+ + H2O→XMP + NADH + H+ (EC 1.1.1.205)
b2508 (guaB)
5'-nucleotidase:
GMP + H2O→guanosine + phosphate (EC 3.1.3.5)
b0480 (ushA)
b2291 (yfbR)
b2744 (surE)
b3399 (yrfG)
b4055 (aphA)
b4374 (yjjG)
Adenosine deaminase:
adenosine + H+ + H2O→inosine + ammonium (EC 3.5.4.4)
b1623 (add)
b2593 (yfiH)
Purine-nucleoside phosphorylase:
guanosine + phosphate→guanine + α-D-ribose-1-phosphate (EC 2.4.2.1; 2.4.2.15)
b0391 (yaiE)
b2407 (xapA)
b4384 (deoD)
5'-nucleotidase:
XMP + H2O→xanthosine + phosphate (EC 3.1.3.5)
b0480 (ushA)
b2291 (yfbR)
b2744 (surE)
b4055 (aphA)
b4374 (yjjG)
Guanine deaminase:
guanine + H+ + H2O→xanthine + ammonium (EC 3.5.4.3)
b2883 (guaD)
Purine-nucleoside phosphorylase:
inosine + phosphate→hypoxanthine + α-D-ribose-1-phosphate (EC 2.4.2.1)
b0391 (yaiE)
b2407 (xapA)
b2593 (yfiH)
b4384 (deoD)
Purine-nucleoside phosphorylase:
xanthosine + phosphate→xanthine + α-D-ribose-1-phosphate (EC 2.4.2.1)
b0391 (yaiE)
b2407 (xapA)
b4384 (deoD)
Xanthine dehydrogenase:
hypoxanthine + NAD+ + H2O→xanthine + NADH + H+ (EC 1.17.1.4)
b0284 (yagR)
b0285 (yagS)
b2866 (xdhA)
b2867 (xdhB)
b2868 (xdhC)
Xanthine dehydrogenase:
xanthine + NAD+ + H2O→urate + NADH + H+ (EC 1.17.1.4)
b0284 (yagR)
b0285 (yagS)
b2866 (xdhA)
b2867 (xdhB)
b2868 (xdhC)

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information