MetaCyc Pathway: partial TCA cycle (obligate autotrophs) in Escherichia coli BW25113

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Phosphoenolpyruvate carboxylase (in reverse):
phosphoenolpyruvate + hydrogen carbonate→oxaloacetate + phosphate (EC 4.1.1.31)
b3956 (ppc)
Citrate (Si)-synthase:
oxaloacetate + acetyl-CoA + H2O→citrate + coenzyme A + H+ (EC 2.3.3.1; 2.3.3.16; 2.3.3.3)
b0720 (gltA)
oxaloacetate[in] + an electron-transfer quinol→(S)-malate[in] + an electron-transfer quinone (EC 1.1.5.4)
b2210 (mqo)
Aconitate hydratase:
citrate→cis-aconitate + H2O (EC 4.2.1.3)
b0118 (acnB)
b0771 (ybhJ)
b1276 (acnA)
Fumarate hydratase:
(S)-malate→fumarate + H2O (EC 4.2.1.2)
b1611 (fumC)
b1612 (fumA)
b1675 (ydhZ)
b2929 (yggD)
b4122 (fumB)
Aconitate hydratase:
cis-aconitate + H2O→D-threo-isocitrate (EC 4.2.1.3)
b0118 (acnB)
b0771 (ybhJ)
b1276 (acnA)
Succinate dehydrogenase (ubiquinone) (in reverse):
fumarate[in] + an electron-transfer quinol→succinate[in] + an electron-transfer quinone (EC 1.3.5.1)
No genes
Isocitrate dehydrogenase (NADP(+)):
D-threo-isocitrate + NADP+→2-oxoglutarate + CO2 + NADPH (EC 1.1.1.42)
b1136 (icd)

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information