MetaCyc Pathway: inosine 5'-phosphate degradation in Escherichia coli BW25113
| IMP dehydrogenase: IMP + NAD+ + H2O→XMP + NADH + H+ (EC 1.1.1.205) |
| b2508 (guaB) |
| 5'-nucleotidase: XMP + H2O→xanthosine + phosphate (EC 3.1.3.5) |
| b0480 (ushA) |
| b2291 (yfbR) |
| b2744 (surE) |
| b4055 (aphA) |
| b4374 (yjjG) |
| Purine-nucleoside phosphorylase: xanthosine + phosphate→xanthine + α-D-ribose-1-phosphate (EC 2.4.2.1) |
| b0391 (yaiE) |
| b2407 (xapA) |
| b4384 (deoD) |
| Xanthine dehydrogenase: xanthine + NAD+ + H2O→urate + NADH + H+ (EC 1.17.1.4) |
| b0284 (yagR) |
| b0285 (yagS) |
| b2866 (xdhA) |
| b2867 (xdhB) |
| b2868 (xdhC) |
Links:
- Pathway details at MetaCyc
- Fitness data for 14 genes
- All MetaCyc pathways for Escherichia coli BW25113
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information