MetaCyc Pathway: pyruvate fermentation to acetate IV in Escherichia coli BW25113
| Formate C-acetyltransferase (in reverse): pyruvate + coenzyme A→acetyl-CoA + formate (EC 2.3.1.54) |
| b0823 (ybiW) |
| b0824 (ybiY) |
| b0902 (pflA) |
| b0903 (pflB) |
| b2579 (yfiD) |
| b3951 (pflD) |
| b3952 (pflC) |
| b3114 (tdcE) |
| Phosphate acetyltransferase: acetyl-CoA + phosphate→acetyl phosphate + coenzyme A (EC 2.3.1.8) |
| b2297 (pta) |
| b2458 (eutI) |
| Acetate kinase (in reverse): acetyl phosphate + ADP→acetate + ATP (EC 2.7.2.1; 2.7.2.15) |
| b1849 (purT) |
| b2296 (ackA) |
| b2460 (eutQ) |
| b2461 (eutP) |
| b3115 (tdcD) |
Links:
- Pathway details at MetaCyc
- Fitness data for 15 genes
- All MetaCyc pathways for Escherichia coli BW25113
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information