MetaCyc Pathway: glutaryl-CoA degradation in Escherichia coli BW25113
glutaryl-CoA + an oxidized electron-transfer flavoprotein + H+→(E)-glutaconyl-CoA + a reduced electron-transfer flavoprotein (EC 1.3.8.6) |
No genes |
(E)-glutaconyl-CoA + H+→crotonyl-CoA + CO2 (EC 1.3.8.6) |
No genes |
crotonyl-CoA + H2O→(S)-3-hydroxybutanoyl-CoA (EC 4.2.1.150) |
b2341 (yfcX) |
b3846 (fadB) |
3-hydroxyacyl-CoA dehydrogenase: (S)-3-hydroxybutanoyl-CoA + NAD+→acetoacetyl-CoA + NADH + H+ (EC 1.1.1.35) |
b2341 (yfcX) |
b3846 (fadB) |
Acetyl-CoA C-acyltransferase (in reverse): acetoacetyl-CoA + coenzyme A→2 acetyl-CoA (EC 2.3.1.16; 2.3.1.9) |
b1397 (paaJ) |
b2224 (atoB) |
b2342 (yfcY) |
b2844 (yqeF) |
b3845 (fadA) |
Links:
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information