MetaCyc Pathway: superpathway of polyamine biosynthesis I in Escherichia coli BW25113

Add experiment(s):


Arginine decarboxylase:
L-arginine + H+→agmatine + CO2 (EC 4.1.1.19)
b2938 (speA)
b4117 (adiA)
Arginase:
L-arginine + H2O→L-ornithine + urea (EC 3.5.3.1)
No genes
Lysine decarboxylase:
L-lysine + H+→cadaverine + CO2 (EC 4.1.1.18)
b0186 (ldcC)
b4131 (cadA)
Adenosylmethionine decarboxylase:
S-adenosyl-L-methionine + H+→S-adenosyl 3-(methylsulfanyl)propylamine + CO2 (EC 4.1.1.50)
b0120 (speD)
Agmatinase:
agmatine + H2O→putrescine + urea (EC 3.5.3.11)
b2937 (speB)
Ornithine decarboxylase:
L-ornithine + H+→putrescine + CO2 (EC 4.1.1.17)
b0693 (speF)
b2965 (speC)
cadaverine + S-adenosyl 3-(methylsulfanyl)propylamine→aminopropylcadaverine + S-methyl-5'-thioadenosine + H+
b0121 (speE)
Spermidine synthase:
putrescine + S-adenosyl 3-(methylsulfanyl)propylamine→spermidine + S-methyl-5'-thioadenosine + H+ (EC 2.5.1.16)
b0121 (speE)

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information