MetaCyc Pathway: superpathway of phospholipid biosynthesis III (E. coli) in Escherichia coli BW25113

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Glycerol-3-phosphate dehydrogenase (NAD(P)(+)) (in reverse):
glycerone phosphate + NAD(P)H + H+→sn-glycerol 3-phosphate + NAD(P)+ (EC 1.1.1.94)
b3608 (gpsA)
Glycerol-3-phosphate O-acyltransferase:
sn-glycerol 3-phosphate + an acyl-[acyl-carrier protein]→a 2-lysophosphatidate + a soluble [acyl-carrier protein] (EC 2.3.1.15)
b1090 (plsX)
b3059 (ygiH)
b4041 (plsB)
Glycerol-3-phosphate O-acyltransferase:
sn-glycerol 3-phosphate + an acyl-CoA→a 2-lysophosphatidate + coenzyme A (EC 2.3.1.15)
b1090 (plsX)
b3059 (ygiH)
b4041 (plsB)
1-acylglycerol-3-phosphate O-acyltransferase:
a 2-lysophosphatidate + an acyl-[acyl-carrier protein]→a phosphatidate + a soluble [acyl-carrier protein] (EC 2.3.1.51)
b3018 (plsC)
b3862 (yihG)
1-acylglycerol-3-phosphate O-acyltransferase:
a 2-lysophosphatidate + an acyl-CoA→a phosphatidate + coenzyme A (EC 2.3.1.51)
b3018 (plsC)
b3862 (yihG)
Phosphatidate cytidylyltransferase:
a phosphatidate + CTP + H+→a CDP-diacylglycerol + diphosphate (EC 2.7.7.41)
b0175 (cdsA)
b1409 (ynbB)
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase:
a CDP-diacylglycerol + sn-glycerol 3-phosphate→a phosphatidylglycerophosphate + CMP + H+ (EC 2.7.8.5)
b1408 (b1408)
b1912 (pgsA)
CDP-diacylglycerol--serine O-phosphatidyltransferase:
a CDP-diacylglycerol + L-serine→a phosphatidylserine + CMP + H+ (EC 2.7.8.8)
b2585 (pssA)
Phosphatidylglycerophosphatase:
a phosphatidylglycerophosphate + H2O→a phosphatidylglycerol + phosphate (EC 3.1.3.27)
b0418 (pgpA)
b1278 (pgpB)
b2560 (yfhB)
Phosphatidylserine decarboxylase:
a phosphatidylserine + H+→a phosphatidylethanolamine + CO2 (EC 4.1.1.65)
b4160 (psd)
2 a phosphatidylglycerol→a cardiolipin + glycerol (EC 2.7.8.41)
b0789 (ybhO)
b1249 (cls)
a phosphatidylethanolamine + a phosphatidylglycerol→a cardiolipin + ethanolamine (EC 2.7.8.41)
b1046 (ymdC)

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information