MetaCyc Pathway: acetylene degradation (anaerobic) in Escherichia coli BW25113
| Acetylene hydratase: acetylene + H2O→acetaldehyde (EC 4.2.1.112) |
| No genes |
| Acetaldehyde dehydrogenase (acetylating): acetaldehyde + coenzyme A + NAD+→acetyl-CoA + NADH + H+ (EC 1.2.1.10) |
| b0351 (mhpF) |
| b1241 (adhE) |
| b2455 (eutE) |
| Alcohol dehydrogenase (in reverse): acetaldehyde + NADH + H+→ethanol + NAD+ (EC 1.1.1.1) |
| b0325 (yahK) |
| b0356 (frmA) |
| b1241 (adhE) |
| b1478 (adhP) |
| b3253 (yhdH) |
| b4269 (yjgB) |
| b3589 (yiaY) |
| Phosphate acetyltransferase: acetyl-CoA + phosphate→acetyl phosphate + coenzyme A (EC 2.3.1.8) |
| b2297 (pta) |
| b2458 (eutI) |
| Acetate kinase (in reverse): acetyl phosphate + ADP→acetate + ATP (EC 2.7.2.1; 2.7.2.15) |
| b1849 (purT) |
| b2296 (ackA) |
| b2460 (eutQ) |
| b2461 (eutP) |
| b3115 (tdcD) |
Links:
- Pathway details at MetaCyc
- Fitness data for 16 genes
- All MetaCyc pathways for Escherichia coli BW25113
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information