MetaCyc Pathway: galactitol degradation in Escherichia coli BW25113
| galactitol[out] + an [HPr protein]-Nπ-phospho-L-histidine[in]→galactitol 1-phosphate[in] + an [HPr]-L-histidine[in] (EC 2.7.1.200) |
| b2092 (gatC) |
| b2093 (gatB) |
| b2094 (gatA) |
| Galactitol-1-phosphate 5-dehydrogenase: galactitol 1-phosphate + NAD+→keto-D-tagatose 6-phosphate + NADH + H+ (EC 1.1.1.251) |
| b2091 (gatD) |
| keto-D-tagatose 6-phosphate→D-tagatofuranose 6-phosphate (spontaneous) |
| No genes |
| Tagatose-6-phosphate kinase: D-tagatofuranose 6-phosphate + ATP→D-tagatofuranose 1,6-bisphosphate + ADP + H+ (EC 2.7.1.144) |
| b1723 (pfkB) |
| b2095 (gatZ) |
| b2168 (fruK) |
| b3132 (kbaZ) |
| b3916 (pfkA) |
| Tagatose-bisphosphate aldolase: D-tagatofuranose 1,6-bisphosphate→glycerone phosphate + D-glyceraldehyde 3-phosphate (EC 4.1.2.40) |
| b2095 (gatZ) |
| b2096 (gatY) |
| b3132 (kbaZ) |
| b3137 (kbaY) |
Links:
- Pathway details at MetaCyc
- Fitness data for 11 genes
- All MetaCyc pathways for Escherichia coli BW25113
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information