MetaCyc Pathway: superpathway of L-aspartate and L-asparagine biosynthesis in Escherichia coli BW25113

Add experiment(s):


Aspartate transaminase (in reverse):
oxaloacetate + L-glutamate→L-aspartate + 2-oxoglutarate
(EC 2.6.1.1)
b0928 (aspC)
b4340 (yjiR)
Aspartate ammonia-lyase (in reverse):
fumarate + ammonium→L-aspartate
(EC 4.3.1.1)
b4139 (aspA)
Aspartate--ammonia ligase:
L-aspartate + ammonium + ATP→L-asparagine + AMP + diphosphate + H+
(EC 6.3.1.1)
b0674 (asnB)
b3744 (asnA)
Asparaginase:
L-asparagine + H2O→L-aspartate + ammonium
(EC 3.5.1.1; 3.5.1.38; 3.5.5.4)
b1767 (ansA)
b2957 (ansB)

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information